Protein Modeling · Division C · Boyceville Invitational · 2018
47 questions · 74 points · 50 min
Original test sourceThere are 20 amino acids that are present in protein structure. Please categorize these 20 amino acids into the following groups by placing either their full name or official 3 letter abbreviations under the appropriate heading. Some amino acids will be placed in more than one group! 10 points.Hydrophobic (Non-polar)
Categorize the 20 amino acids under the heading:
Hydrophilic (Polar)
Categorize the 20 amino acids under the heading:
Acidic
Categorize the 20 amino acids under the heading:
Basic
20 amino acids are required for synthesis of various proteins found in humans. However, we can synthesize only ____ naturally.
How do we obtain the remaining amino acids? ____
Which one of the following statements is correct?
Amino acids are mostly synthesized from
The unique properties of each amino acid are determined by its particular
A peptide bond
Which of the following is NOT a function of hemagglutinin (HA)?
How many of the 12+ subtypes of hemagglutinin attack humans?
Amino acids are acids because they always possess which functional group?
Upon chemical analysis, a particular polypeptide was found to contain 100 amino acids. How many peptide bonds are present in this protein?
Which bonds are created during the formation of the primary structure of a protein?
What maintains the secondary structure of a protein?
The tertiary structure of a protein is the
At which level of protein structure are interactions between the side chains (R groups) most important?
What would be an unexpected consequence of changing one amino acid in a protein consisting of 325 amino acids?
Which best describes the influenza virus?
How many strands of genetic material are found inside of the influenza virus?
The receptor binding site on hemagglutinin binds to
What is the name of the reaction in which a peptide bond is formed?
Which class of amino acids will most likely be located on the surface of a protein that is embedded within the phospholipid cell membrane?
Which of the following are NOT found in a protein:
Which hemagglutinin subtype attacks proteins in the digestive system of birds? ____
Two main types of secondary structure are ____ and ____.
Approximately how many people die from the influenza virus (or rather complications of) every year in the US? ____
Name the four major flu pandemics, with their corresponding years:
H1N1 typically leads to the death of affected birds within ____ hours.
The protein coat of a virus is called its ____.
What do we inject a virus into to amplify it to create enough for a vaccine? ____
Hemagglutinin is made up primarily of ____ (#) monomers.
Explain a situation that might cause the Avian Influenza (H5N1) virus to become dangerous to humans.
What is the function of the ribonucleoprotein (or M1 Matrix Protein)?
How do enveloped viruses penetrate cells?
Why are viruses considered obligate internal parasites?
Where does a virus usually get it's envelope from?
What is the function of neuraminidase?
Explain how an endosome forms, and how a virus uses an endosome.
What is virulence, and what specific parts of hemagglutinin are involved in making the virus more virulent or pathogenic?
What amino acid changes its charge between a pH of 7 and a pH of 5 (that is especially important in the conformational change of hemaggutinin)?
Explain the relationship between Tamiflu and neuraminidase.
Explain the relationship between hemagglutinin and sialic acid sugars.
Where does hemagglutinin get its name?
What are the three main functions of hemagglutinin?
How many different subtypes of neuraminidase are there?